Colonoscopy in asymptomatic individuals with a family history of colorectal cancer

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Abstract
A prevalence screening porgram with colonoscopy was undertaken in 4 kindreds manifesting the cancer family syndrome. Of counseled patients, 45% underwent colonoscopy, proving 42 asymptomatic individuals. Seven patients (17%) were found to have adenomatous or villous polyps; 2 of these were malignant and 1 showed epithelial atypia. Three of the 7 patients with polyps had multiple lesions. Only 2 patients had rectosigmoid polyps. From these limited data, colonoscopy is recommended as a usefuul screening procedure in individuals at high risk for colorectal cancer.