CO Laser Angioplasty Using Contact Irradiation

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Abstract
We successfully demonstrated usefulness of CO laser angioplasty. We investigated in vivo CO laser angioplasty using contact irradiation under visualization by a thin endoscope in atheromatous rabbit aorta, which was temporary filled by saline during the irradiation. 4W, 4s contact irradiation via 400μm As-S glass fiber to atheromatous aorta wall made a fine ablation hole with the minimum heat injuries to remained vascular tissue. A small amount of char was found on ZnSe contact tip after approximately 20 irradiations. But no damage was occurred in the tip. We think the visualization in the arterial lumen by the thin endoscope may be useful for pre-diagnosis and targeting of laser therapy.

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