Long‐term follow‐up of patients with epithelial carcinoma of the ovary

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Abstract
OBJECTIVES: To determine the long‐term outcomes of patients with epithelial ovarian cancer. METHODS: A group of 298 patients with epithelial ovarian cancer were treated with combination chemotherapy between July 1979 and January 1986 at the Tokai Ovarian Tumor Study Group. Long‐term results of these patients were analyzed. RESULTS: Five‐year survival and 10‐year survival rates of all the patients were 53% and 47%, respectively. Five‐year survival and 10‐year survival rates for stage I were 89% and 79%, 59% and 56% for stage II, 27% and 22% for stage III, and 9% and 9% for stage IV, respectively. Survival of mucinous and endometrioid cell types were decreased after 5 or more years. In stages II‐IV, cisplatin‐based chemotherapy produced better results than mitomycin‐C, 5‐Fu, cytarabine (MFC) therapy. CONCLUSIONS: Long‐term results of epithelial ovarian cancer were not favorable even in mucinous and endometrioid cell types. For long‐term results, cisplatin‐based chemotherapy was effective in advanced ovarian cancer. Long‐term follow‐up of ovarian cancer is important and necessary.

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