Lactase activity is under hormonal control in the intestine of adult rat.
Open Access
- 1 July 1983
- Vol. 24 (7) , 648-652
- https://doi.org/10.1136/gut.24.7.648
Abstract
In the adult rat, starvation during 48 hours led to a three fold increase of lactase specific activity in the intestinal brush border membranes. Thyroxine injection during the three days before death (0.5 micrograms/g daily) inhibited the stimulation of lactase activity induced by starvation without modifying sucrase activity whereas hydrocortisone injections (25 micrograms/g daily) or thyroidectomy did not modify the stimulatory effect of starvation on lactase activity. These results suggests a specific hormonal control of intestinal lactase activity in the rat.Keywords
This publication has 27 references indexed in Scilit:
- Effects of prolonged alcohol administration and a high carbohydrate-low protein diet on the activities of the jejunal brush border enzymes in the rat.Gut, 1982
- Dietary‐induced rapid increase of rat jejunal sucrase and lactase activity in all regions of the villusFEBS Letters, 1981
- Early changes in brush border disaccharidase kinetics in rat jejunum following subcutaneous administration of tetraiodothyronineHistochemistry and Cell Biology, 1981
- Site of Substrate Stimulation of Jejunal Sucrase in the RatJournal of Clinical Investigation, 1979
- Relationship between the changes in gastrin levels and intestinal properties in the starved ratDigestive Diseases and Sciences, 1976
- A method for the separate assay of “neutral” and “acid” β-galactosidase in homogenates of rat small-intestinal mucosaAnalytical Biochemistry, 1969
- Effect of Diet upon Intestinal Disaccharidases and Disaccharide Absorption*Journal of Clinical Investigation, 1967
- A one-step ultramicro method for the assay of intestinal disaccharidasesAnalytical Biochemistry, 1966
- Intestinal disaccharidase activities in adult and suckling ratsBiochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964
- Studies of small intestine during development I. Distribution and activity of ß-galactosidaseBiochimica et Biophysica Acta, 1962