Effect of an LHRH‐agonist on testicular microcirculation in hypophysectomized rats
Open Access
- 1 December 1987
- journal article
- research article
- Published by Wiley in International Journal of Andrology
- Vol. 10 (6) , 785-791
- https://doi.org/10.1111/j.1365-2605.1987.tb00382.x
Abstract
Summary: The effect of an LHRH‐agonist on testicular vasomotion was studied in adult hypophysectomized rats. At 0.5 and 1 h after injection of 1 μg LHRH‐agonist, no effect on vasomotion was observed, but after 2 h the pulsatile blood flow pattern had changed to continuous flow in 50% of the rats. At 4 h after treatment with LHRH‐agonist, vasomotion was not detected in the testis of any rat. In addition, at the latter time an increased number of polymorphonuclear leucocytes (PMNs) were observed in testicular microvessels, and some PMNs had migrated into the interstitial space. These findings are discussed in relation to the well‐known stimulatory effect of LHRH‐agonists on testicular interstitial fluid volume.Keywords
This publication has 21 references indexed in Scilit:
- Treatment of rats with hCG induces inflammation-like changes in the testicular microcirculationReproduction, 1987
- Testicular vascular resistance in the rat after intratesticular injection of an LRH‐agonistInternational Journal of Andrology, 1986
- Testicular microcirculation in the rat studied by videophotometric capillaroscopy, fluorescence microscopy and laser Doppler flowmetryActa Physiologica Scandinavica, 1986
- Stimulatory effect of an LHRH-agonist on testicular blood flow in hypophysectomized ratsInternational Journal of Andrology, 1984
- Intratesticular Factors Controlling Testicular FunctionBiology of Reproduction, 1984
- Stimulation of leydig cell testoterone secretion in vitro and in vivo in hypophysectomized rats by an agonist of luteinizing hormone releasing hormoneBiochemical and Biophysical Research Communications, 1982
- EFFECT OF INJECTED HUMAN CHORIONIC GONADOTROPHIN ON CAPILLARY PERMEABILITY, EXTRACELLULAR FLUID VOLUME AND THE FLOW OF LYMPH AND BLOOD IN THE TESTES OF RATSJournal of Endocrinology, 1981
- Inhibitory Effect of Estradiol-17β on Human Chorionic Gonadotropin- Induced Increment of Testicular Blood Flow and Plasma Testosterone Concentration in RatsBiology of Reproduction, 1981
- Temporal Relationship Between Interstitial Fluid Accumulation and Changes in Gonadotropin Receptor Numbers and Steroidogenesis in the Rat TestisBiology of Reproduction, 1980
- Relationship between testosterone, fluid content and luteinizing hormone receptors in the rat testisBiochemical and Biophysical Research Communications, 1977