Cellular Arrhythmogenic Effects of Congenital and Acquired Long-QT Syndrome in the Heterogeneous Myocardium
- 14 March 2000
- journal article
- other
- Published by Wolters Kluwer Health in Circulation
- Vol. 101 (10) , 1192-1198
- https://doi.org/10.1161/01.cir.101.10.1192
Abstract
Background—Certain alterations by mutations or drugs of the potassium currents IKs and IKr and the sodium current INa give rise to several types of the long-QT syndrome. IKs is heterogeneously dist...Keywords
This publication has 10 references indexed in Scilit:
- Linking a genetic defect to its cellular phenotype in a cardiac arrhythmiaNature, 1999
- Pause induced early afterdepolarizations in the long QT syndrome: a simulation studyCardiovascular Research, 1999
- Heterogeneous Loss of Connexin43 Protein in Ischemic Dog HeartsJournal of Cardiovascular Electrophysiology, 1999
- The impact of adjusting for post-test referral bias on apparent sensitivity and specificity of SPECT myocardial perfusion imaging in men and womenJournal of the American College of Cardiology, 1998
- Multiple effects of KPQ deletion mutation on gating of human cardiac Na+channels expressed in mammalian cellsAmerican Journal of Physiology-Heart and Circulatory Physiology, 1998
- Molecular mechanism for an inherited cardiac arrhythmiaNature, 1995
- Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: Evidence for presence of M cellsJournal of the American College of Cardiology, 1995
- Early afterdepolarizations in cardiac myocytes: mechanism and rate dependenceBiophysical Journal, 1995
- A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes.Circulation Research, 1994
- Drug‐Induced Afterdepolarizations and Triggered Activity Occur in a Discrete Subpopulation of Ventricular Muscle Cells (M Cells) in the Canine Heart:Journal of Cardiovascular Electrophysiology, 1993