The interaction of nucleotides with pertussis toxin. Direct evidence for a nucleotide binding site on the toxin regulating the rate of ADP-ribosylation of Ni, the inhibitory regulatory component of adenylyl cyclase.
Open Access
- 1 August 1986
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 261 (24) , 11173-11179
- https://doi.org/10.1016/s0021-9258(18)67364-8
Abstract
No abstract availableThis publication has 27 references indexed in Scilit:
- Effects of guanine nucleotides and Mg on human erythrocyte Ni and Ns, the regulatory components of adenylyl cyclase.Journal of Biological Chemistry, 1984
- G proteins and dual control of adenylate cyclaseCell, 1984
- Forskolin regulation of liver membrane adenylyl cyclaseEuropean Journal of Biochemistry, 1983
- Pertussis toxin substrate, the putative Ni component of adenylyl cyclases, is an alpha beta heterodimer regulated by guanine nucleotide and magnesium.Proceedings of the National Academy of Sciences, 1983
- The A protomer of islet-activating protein, pertussis toxin, as an active peptide catalyzing ADP-ribosylation of a membrane proteinArchives of Biochemistry and Biophysics, 1983
- Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteinsNature, 1983
- A procedure for rapid extraction and high-pressure liquid chromatographic separation of the nucleotides and other small molecules from bacterial cellsAnalytical Biochemistry, 1982
- Direct modification of the membrane adenylate cyclase system by islet-activating protein due to ADP-ribosylation of a membrane protein.Proceedings of the National Academy of Sciences, 1982
- The enzymatic preparation of [α-32P]nucleoside triphosphates, cyclic [32P]AMP, and cyclic [32P]GMPBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1979
- Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase systemProceedings of the National Academy of Sciences, 1978