PARA-INFLUENZA 2 (CA) VIRUS: ETIOLOGIC ASSOCIATION WITH CROUP

Abstract
During October, November and December, 1959, para-influenza 2, or croup-associated (CA), virus was recovered from 7 of 28 patients with croup. Three additional patients were infected with this agent, as indicated by serologic tests. The incidence of virus recovery from patients with croup was many times greater than from comparable control infants and children, regardless of the attribute compared. These findings constitute the first evidence from controlled epidemiologic studies that para-influenza 2 virus has an etiologic relationship to the croup syndrome. They also indicate the variable prevalence of para-influenza 2 virus, which differs from the almost constant presence of para-influenza 3 virus and para-influenza 1 virus in the pediatric population under study.
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