Intranodal Leiomyoma: Another Distinctive Primary Spindle Cell Neoplasm of Lymph Node

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Abstract
Two intranodal spindle cell neoplasms are described that were interpreted as leiomyomas. Both occurred in young men. The first case involved a single peripancreatic lymph node of a patient with acquired immune deficiency syndrome (AIDS) who died of AIDS-related infection. The second case simulated a parotid gland tumor because of its location in an intraparotid lymph node in an otherwise asymptomatic patient. Both neoplasms were composed of interlacing fascicles of spindle cells with blunt-ended nuclei that seemed to arise from the walls of blood vessels. The tumor cells were immunoreactive for muscle-specific actin but were desmin negative. These leiomyomas expand the clinical and morphologic spectrum of primary spindle cell neoplasms of lymph nodes.

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