CNS gene transfer mediated by a novel controlled release system based on DNA complexes of degradable polycation PPE-EA: a comparison with polyethylenimine/DNA complexes
Open Access
- 18 December 2003
- journal article
- research article
- Published by Springer Nature in Gene Therapy
- Vol. 11 (1) , 109-114
- https://doi.org/10.1038/sj.gt.3302135
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cordGene Therapy, 2003
- Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrierGene Therapy, 2002
- Tumor targeting with surface-shielded ligand–polycation DNA complexesJournal of Controlled Release, 2001
- Transgene Expression in the Brain Stem Effected by Intramuscular Injection of Polyethylenimine/DNA ComplexesMolecular Therapy, 2001
- Nonviral Gene Delivery to the Lateral Ventricles in Rat Brain: Initial Evidence for Widespread Distribution and Expression in the Central Nervous SystemMolecular Therapy, 2001
- Intra-CSF administered recombinant adenovirus causes an immune response-mediated toxicityGene Therapy, 2000
- Evaluation of polyether-polyethyleneimine graft copolymers as gene transfer agentsGene Therapy, 2000
- Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous systemGene Therapy, 1998
- A Powerful Nonviral Vector for In Vivo Gene Transfer into the Adult Mammalian Brain: PolyethylenimineHuman Gene Therapy, 1996
- Polyethylenimine-Mediated DNA Transfection of Peripheral and Central Neurons in Primary Culture: Probing Ca2+Channel Structure and Function with Antisense OligonucleotidesMolecular and Cellular Neuroscience, 1996