Stability of antimicrobials in Schaedler's anaerobic and brain heart infusion broths stored at -20.DEG.C.
- 1 January 1978
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 31 (3) , 226-228
- https://doi.org/10.7164/antibiotics.31.226
Abstract
Penicillin-like drugs are unstable in Schaedler''s broth in frozen storage (-20.degree. C). Chloramphenicol, clindamycin and tetracycline remained at original potency to 45 days. No detectable antimicrobial decay was found in 2 formulations of supplemented BHI [brain heart infusion] broth. Antimicrobial [antibacterial] potency was measured by quality control orgainism endpoints, bioassays and MIC [minimum inhibitory concentration] changes in use at 4 clinical microbiology laboratories.This publication has 0 references indexed in Scilit: