A new route to 5-bromo-5′-bromomethylpyrromethenes

Abstract
Esters of hitherto inaccessible 5-bromo-5′-bromomethylpyrromethenes, with alternating acetic acid (or methyl) and propionic acid groups in the (β positions, are obtained by brominating the appropriate 5-acetoxymethylpyrrole-2-carboxylic acids in ethanol-free chloroform at ≤10 °C. The bromomethylpyrromethenes give the corresponding methoxymethylpyrromethenes in methanol at room temperature.

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