HLA-B27 and acute anterior uveitis
- 1 January 1990
- journal article
- review article
- Published by Taylor & Francis in Current Eye Research
- Vol. 9 (sup1) , 213-218
- https://doi.org/10.3109/02713689008999444
Abstract
This article reviews the ophthalmological significance of the association between HLA-B27 and acute anterior uveitis (AAU). HLA-B27 determination should be performed in all cases of acute anterior uveitis (AAU), since B27+ AAU is a distinct kind of uveitis. All B27+ AAU patients have to be referred to a rheumatologist because half of these patients has ankylosing spondylitis or Reiter's syndrome. The structure and physiological role of HLA-class I molecules is now known. It is probable that the role of HLA-B27 in the pathogenesis of AAU will be revealed in the coming years.Keywords
This publication has 6 references indexed in Scilit:
- B27 positive diseases versus B27 negative diseases.Annals of the Rheumatic Diseases, 1988
- Structure of the human class I histocompatibility antigen, HLA-A2Nature, 1987
- Autoantibodies to HLA B27 in the sera of HLA B27 patients with ankylosing spondylitis and Reiter's syndrome. Molecular mimicry with Klebsiella pneumoniae as potential mechanism of autoimmune disease.The Journal of Experimental Medicine, 1987
- beta2 Microglobulin Enhances the Infectivity of Cytomegalovirus and When Bound to the Virus Enables Class I HLA Molecules To Be Used as a Virus ReceptorJournal of General Virology, 1987
- Clinical Features of Acute Anterior UveitisAmerican Journal of Ophthalmology, 1987
- The use of HLA-B27 as a diagnostic and prognostic aid in acute anterior uveitis (AAU) in the NetherlandsDocumenta Ophthalmologica, 1987