Inverse agonist properties of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide HCl (SR141716A) and 1-(2-chlorophenyl)-4-cyano-5-(4-methoxyphenyl)-1H-pyrazole-3-carboxylic acid phenylamide (CP-272871) for the CB1 cannabinoid receptor
- 1 November 2000
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 60 (9) , 1315-1323
- https://doi.org/10.1016/s0006-2952(00)00447-0
Abstract
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This publication has 20 references indexed in Scilit:
- SR141716A, a potent and selective antagonist of the brain cannabinoid receptorPublished by Wiley ,2001
- Inverse agonism: pharmacological curiosity or potential therapeutic strategy?Published by Elsevier ,2000
- Potential Biosynthetic Connections between the Two Cannabimimetic Eicosanoids, Anandamide and 2-Arachidonoyl-Glycerol, in Mouse Neuroblastoma CellsBiochemical and Biophysical Research Communications, 1996
- Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma ‘anandamide amidohydrolase’FEBS Letters, 1995
- Endogenous ligands and inverse agonismTrends in Pharmacological Sciences, 1995
- Pharmacology of Cannabinoid ReceptorsAnnual Review of Pharmacology and Toxicology, 1995
- Precoupling of GiGo-linked receptors and its allosteric regulation by monovalent cationsLife Sciences, 1993
- Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid ReceptorScience, 1992
- Reverse intrinsic activity of antagonists on G protein-coupled receptorsTrends in Pharmacological Sciences, 1992
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976