Late onset Leber's optic neuropathy: a case confused with ischaemic optic neuropathy.
Open Access
- 1 September 1992
- journal article
- case report
- Published by BMJ in British Journal of Ophthalmology
- Vol. 76 (9) , 571-573
- https://doi.org/10.1136/bjo.76.9.571
Abstract
A case is reported of a 63-year-old man with progressive central visual loss in one eye followed 11 months later by involvement of the fellow eye. A diagnosis of chronic ischaemic optic neuropathy was considered. However, despite a negative family history, the absence of electrocardiographic abnormalities, and minimal fundus changes a diagnosis of Leber's optic neuropathy was made on the basis of magnetic resonance imaging findings and the mitochondrial DNA mutation at base pair 11778.Keywords
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