Seeking the Cause of Induced Leukemias in X-SCID Trial
- 24 January 2003
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 299 (5606) , 495
- https://doi.org/10.1126/science.299.5606.495
Abstract
Details of a second case of cancer in a gene-therapy trial in France, revealed last week, raise the odds that both were therapy induced. In both cases, a retrovirus engineered to shuttle corrective genes into cells inserted itself in or near a cancer-causing gene, apparently triggering uncontrolled cell growth.Keywords
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