Abstract
Patients with advanced epidermoid carcinoma of the head and neck are often treated with combinations of radiation therapy and surgery. Patients with more advanced malignancies may also receive adjuvant chemotherapy. Prospective randomized protocols provide the most effective means of determining the value of combined modalities versus a single modality only. Preoperative assessment includes direct visualization, palpation, endoscopy and, in selected incidents, CT or MRI scanning. CT scan may provide objective evidence of tumor response when preoperative adjuvant treatment, either as radiation or chemotherapy, is given.

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