Reversibility of severe bleomycin-induced pneumonitis
- 12 May 1978
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 239 (19) , 2012-2014
- https://doi.org/10.1001/jama.239.19.2012
Abstract
The use of bleomycin sulfate as an antineoplastic agent is limited by its substantial pulmonary toxic effects. The exact incidence and prognosis of bleomycin-pneumonitis is unresolved. Although bleomycin pulmonary toxicity is thought to be dose-related, recent reports have emphasized severe reactions at low doses. Furthermore, severe pulmonary toxicity is suggested to be progressive, irreversible and ultimately, fatal. Clinical, roentgenographic and pathophysiologic recovery after severe bleomycin-induced pneumonitis is reported.This publication has 2 references indexed in Scilit:
- Bleomycin, an Antitumor AntibioticAnnals of Internal Medicine, 1972
- The Spectrum of Drug-Induced Pulmonary DiseaseAnnals of Internal Medicine, 1972