VIRAL INFECTIONS OF TORONTO CHILDREN DURING 1965 .I. ENTEROVIRAL DISEASE

  • 1 January 1966
    • journal article
    • research article
    • Vol. 94  (16) , 839-+
Abstract
Enteroviruses were isolated from feces and/or cerebro-apinal fluid of 29 of 43 Toronto children who contracted aseptic meningitis, pleurodynia, abdominal pain or febrile upsets between June and October, 1965. Coxsackie A9 virus was the dominant agent in aseptic meningitis and Coxsackie Bl virus in pleurodynia and other syndromes, Serological evidence of recent Coxsackie Bl and Echo 6 infection was obtained in 2 additional patients with aseptic meningitis who did not yield virus, and elevated Coxsackie Bl antibody titers were found in 1 patient with pericarditis. A newborn infant died with myocarditis due to Coxsackie Bl virus following infection of the mother during the immediate antenatal period. Paired sera collected only 2 to 4 days apart from patients with enteroviral syndromes or mumps meningo-encephalitis frequently showed 4-fold or greater increases of antibody levels.