Thrombocytopenic Episodes in Patients with Well-Functioning Renal Allografts
- 1 January 1979
- journal article
- research article
- Published by S. Karger AG in Acta Haematologica
- Vol. 61 (1) , 2-9
- https://doi.org/10.1159/000207619
Abstract
20 out of 50 patients with well-functioning renal allograft displayed at least one platelet count below 110×109/1 (mean -2 SD of controls). For estimation of platelet production during thrombocytopenic episodes, the percentage of large platelets in the peripheral blood was determined which revealed an inverse relationship (p < 0.01) to the platelet count, indicating that these thrombocytopenias were due to increased platelet consumption. Immunosuppressive treatment as well as rejection processes could be excluded as major pathogenetic factors whereas anti-platelet autoantibodies may contribute to this phenomenon.Keywords
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