Octahydro-7(1H)-quinolones. II. A stereoselective synthesis of cis-octahydro-7(1H)-quinolone.
- 1 January 1977
- journal article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 25 (7) , 1797-1802
- https://doi.org/10.1248/cpb.25.1797
Abstract
Cis-Octahydro-7 (1H)-quinolone (III) was synthesized stereoselectively by two different routes, one via intramolecular Michael addition of an amino enone (IV) and the other via catalytic hydrogenation of a bicyclic lactam (V). Detailed examinations of hydrogenation products in the latter was also described.Keywords
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