Extragenic Suppression of a ts Phenotype During Recombination Between ts Mutants of Two Fowl Plague Virus Strains with a ts Mutation in Gene 1

Abstract
Fowl plaque virus (FPV) ts mutants belonging to 6 recombination groups and obtained from the Weybridge strain (in the USSR) or the Rostock strain (in the UK) were studied in a recombination test. Temperature-sensitive mutants obtained from different FPV strains were revealed which had a ts mutation in gene 1; their crossing resulted in ts+ recombinants which appeared with a high frequency. This phenomenon was due not to intragenic complementation but to extragenic suppression, when the expression of a ts phenotype of the Rostock strain mutant gene 1 is suppressed by gene 2 products of the Weybridge strain.

This publication has 11 references indexed in Scilit: