HYPERSENSITIVITY TO ISONIAZID - REPORT OF A CASE WITH DISCUSSION OF MANAGEMENT AND ORAL DESENSITIZATION

1 January 1962

journal article
research article
Published by Elsevier

Vol. 85 (1) , 100-+
https://doi.org/10.1164/arrd.1962.85.1.100

Abstract

A case of hyper-sensitivity to isoniazid, manifested by fever, malaise, headache, anorexia, dermatitis, lymphadenopathy, eosinophilia, and anicteric hepatitis, has been presented. After oral desensitization over a fifty-two-day period the patient was able to tolerate full doses of the drug. A detailed description is given of the management of hypersensitivity to isoniazid, with particular emphasis on desensitization.

Keywords

This publication has 2 references indexed in Scilit:

PROBABLE HEPATIC ALLERGY TO CHLORPROMAZINE AND DELIBERATE DESENSITIZATION
Annals of Internal Medicine, 1960
COMBINED HYPERSENSITIVITY REACTION TO SODIUM PARA-AMINOSALICYLATE AND ASSOCIATED ANTIBACTERIAL DRUG CONCURRENTLY ADMINISTERED
Annals of Internal Medicine, 1957