ALCOHOLIC HYALIN‐LIKE BODIES FOUND IN THE PANCREATIC ACINAR CELLS AND NERVE CELLS OF THE BRAIN

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Abstract
The presence of hyalinoid body as an eosinophilic, dendriform to irregularly shaped mass was noted in the cytoplasm of pancreatic acinar cells of 13 among a series of approximately 150 autopsy cases of alcoholism examined. Similar subcellular structures were also demonstrable in nerve cells of the brain in 2 of these cases. The hyalinoid body stained scarlet in phloxine methylene blue preparations and orange‐brown in preparations with the Masson staining method (modified procedure of Gomori), and was revealed to be a fibrillar filamentous mass by electron microscopy. These characteristics suggest its marked resemblance to alcoholic hyalin in liver cells.

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