Comparative studies of ‘bile salts’. 6. Partial synthesis of coprostanic acid, a ‘stem acid’ of primitive bile salts
- 1 December 1952
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 52 (4) , 588-590
- https://doi.org/10.1042/bj0520588
Abstract
Cholanic acid was converted by a malonic ester synthesis to coprostan-26-oic acid. The intermediates and by-products of this partial synthesis were isolated and characterized. Coprostanic acid was shown to be identical with the C27 stem acid previously made from the bile salts of Crocodylidae; it should be a useful reference compound.Keywords
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- Comparative studies of ‘bile salts’. 5. Bile salts of CrocodylidaeBiochemical Journal, 1952