EVALUATION OF THE NEED FOR PROPHYLACTIC ANTIPARKINSONIAN MEDICATION IN PSYCHOTIC-PATIENTS TREATED WITH NEUROLEPTICS

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  • 1 March 1986
    • journal article
    • research article
    • Vol. 47  (3) , 114-116
Abstract
A double-blind study of 42 psychotic patients treated with neuroleptics evaluated the need for prophylactic use of antiparkinsonian medication. The patients assigned to placebo (N = 27) presented significantly more severe extrapyramidal symptomatology, particularly dystonias, than those given trihexyphenidyl (N = 15), indicating a need for the prophylactic use of antiparkinsonian medication during treatment with neuroleptics.