LOCAL IMMUNITY IN PIG RESPIRATORY-TRACT .1. CELLULAR AND HUMORAL IMMUNE-RESPONSES FOLLOWING SWINE INFLUENZA INFECTION

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  • 1 January 1977
    • journal article
    • research article
    • Vol. B128  (1) , 95-107
Abstract
By serial lung washings on living pigs, the kinetics of humoral and cellular local immune responses were studied following intranasal inoculation of swine influenza virus. Local and serum antibodies appeared 8 days post-infection (p.i.) and reached a maximal titer 2 wk p.i. The antibody titer decreased faster in lung secretions than in serum. Local and systemic cell-mediated immune responses were detected, by in vitro transformation tests, during the 2nd wk p.i.