RADIOIODINE UPTAKE IN SUBACUTE THYROIDITIS DEVELOPING IN AN ENVIRONMENT OF ENDEMIC GOITRE

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Abstract
Radioiodine parameters, mainly 131I uptake by the thyroid gland were reviewed in 31 cases of subacute thyroiditis (SAT). Seven cases presented depressed uptake. The remainder had either normal or high uptakes regardless of the phase during which the measurements were made. Fifteen subjects had lived in endemic goiter areas and 16 were from Buenos Aires where 131I uptakes are high and subendemic conditions prevail. Under these circumstances the inhibitory effect of SAT on 131I uptake as usually seen, does not become evident. PB131I and BE131I [butanol extractable iodine] were normal in the subjects with normal or high 131I uptakes. Radioiodine parameters in an endemic environment do not contribute to the diagnosis of SAT. The pathophysiology of SAT is discussed in the view of the present and related studies.

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