HYPOXAEMIA AND PAIN RELIEF AFTER LOWER ABDOMINAL SURGERY: COMPARISON OF EXTRADURAL AND PATIENT-CONTROLLED ANALGESIA
- 1 December 1992
- journal article
- clinical trial
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 69 (6) , 554-557
- https://doi.org/10.1093/bja/69.6.554
Abstract
We have examined postoperative pain in patients allocated randomly to receive extradural bolus diamorphine 3.6 mg, extradural infusion of 0.15% bupivacaine with 0.01% diamorphine or patient-controlled i.v. administration of diamorphine at a maximum rate of 1 mg per 5 min, after total abdominal hysterectomy. Extradural infusion analgesia produced the smallest pain scores from 12 to 24 h after surgery (P < 0.05). More patients in the extradural infusion group were moderately hypoxaemic (SpO2 < 90% > 12 min h-1) after operation, compared with the two other groups (P < 0.05). The group using patient-controlled analgesia received more diamorphine and suffered a greater incidence of emetic sequelae (P < 0.05).Keywords
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