PERIPHERAL BLOOD FLOW IN SCHIZOPHRENIA AND OTHER ABNORMAL MENTAL STATES

Abstract
The peripheral circulation in schizophrenia has recently been the subject of a number of investigations. Olkon,1in a study of the character of the cutaneous capillaries in a large series of schizophrenic subjects, concluded that there were a definite deficiency and typical morphologic abnormalities in this portion of the vascular bed, the severity of the disease being related to the degree of derangement. Freeman,2investigating circulation time in normal and in schizophrenic subjects, found that the schizophrenic group was characterized by an abnormally slow and highly variable rate of blood flow. On the other hand, Gottlieb3presented evidence that the circulation time was normal in this disease. Other studies on schizophrenic subjects have indicated a certain degree of dysfunction of the autonomic nervous system, as suggested by abnormal responses to exposure to cold and hot baths,4to warm air5and to the intravenous administration of

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