Antigens common to Types 1 and 2 poliomyelitis viruses
- 1 September 1961
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 59 (3) , 349-355
- https://doi.org/10.1017/s0022172400039012
Abstract
During a recent epidemic of poliomyelitis three viruses isolated (one Type 1 and two Type 2) elicited both Type 1 and Type 2 CF and precipitating antibodies in the patients whilst only the homotypic neutralizing antibodies were present. These viruses inoculated into animals produced specific CF and neutralizing antibodies, but precipitating antibodies to both types were present in a significant number of animals. These findings suggest that certain polioviruses have complement-fixing and precipitating antigens common to both Type 1 and Type 2 viruses.We would like to thank our colleagues in the Virus Research Unit for their helpful advice and criticism and Dr J. Hampton (Poliomyelitis Inst., Johannesburg) for the concentrated Type 1 poliovirus vaccine.Keywords
This publication has 2 references indexed in Scilit:
- The use of new antigens in the complement-fixation test for acute poliomyelitisEpidemiology and Infection, 1960
- Studies on poliomyelitis virus. Concentration and purification of the virusEpidemiology and Infection, 1957