Blood Selenium Levels and Glutathione-Peroxidase Activities in University and Chronic Intravenous Hyperalimentation Subjects

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Abstract
Se concentration was determined in erythrocytes and plasma and these values were compared to the measured erythrocyte glutathione-peroxidase activity for a university and a long-term i.v. hyperalimentation (IVH) population. These chronic IVH patients were possibly at risk for Se deficiency. There was a positive correlation (r = 0.67) between erythrocyte Se levels and erythrocyte glutathione-peroxidase activities in the university population. The patients receiving IVH had significantly lower mean Se levels in erythrocytes and plasma and mean glutathione-peroxidase activities than the values from the university population. No correlation existed between erythrocyte Se levels and erythrocyte glutathione-peroxidase activities in this IVH patient population. These chronic IVH patients when compared with the university population appear to be at risk for Se deficiency.