PARINAUD'S OCULOGLANDULAR SYNDROME DUE TO A YEASTLIKE ORGANISM

1 June 1945

journal article
research article
Published by American Medical Association (AMA) in Archives of Ophthalmology (1950)

Vol. 33 (6) , 471-475
https://doi.org/10.1001/archopht.1945.00890180069007

Abstract

At the present time it is well established that what was first known as Parinaud's conjunctivitis, after its description by that author in 1889, is not a definite disease with specific pathologic and bacteriologic characteristics, but is in reality a symptom complex which can be caused by a number of etiologic factors. For that reason the term "Parinaud's oculoglandular syndrome,"¹ for a chronic uniocular granulomatous conjunctivitis with regional lymphadenitis, appears most appropriate. Tularemia, tuberculosis, an unidentified virus infection, lymphogranuloma venereum, syphilis and even infections with the hemolytic staphylococcus and Bacillus proteus,² have been listed as causes of the condition. But by far the most common agent appears to be the leptothrix, first found in pathologic sections by Verhoeff, in 1913³ and later obtained in cultures of conjunctival material by Verhoeff and King, in 1933.⁴ Others have confirmed these observations and have also demonstrated the organism in

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