Immunohistochemical study of C cell follicles in dog thyroid glands
- 1 September 1982
- journal article
- research article
- Published by Wiley in The Anatomical Record
- Vol. 204 (1) , 55-60
- https://doi.org/10.1002/ar.1092040108
Abstract
In dog thyroid glands there are C cell follicles which are lined solely by C cells and which accumulate a colloidlike substance in the luminal cavities. In order to clarify the properties of the colloidlike substance secreted by C cells, the C cell follicles were stained with PAS reaction and immunoperoxidase method using anticalcitonin, anti‐C‐thyroglobulin, and anti‐19S‐thyroglobulin antisera, respectively. The colloidlike substance was PAS positive and revealed the strong immunoreaction for C‐thyroglobulin but a faint reaction for calcitonin. It was nonreactive with anti‐19‐thyroglobulin antiserum. These results confirm that C cells synthesize the glycoprotein immunoreactive to anti‐C‐thyroglobulin antiserum in addition to calcitonin and can store it in the follicular lumens.Keywords
This publication has 14 references indexed in Scilit:
- Uptake of radioiodine in follicles of dog C-cell complexes studied by autoradiograph and immunoperoxidase stainingThe Anatomical Record, 1981
- Development and cytodifferentiation of C cell complexes in dog fetal thyroidsCell and tissue research, 1980
- Immunohistochemical study of the medullary thyroid carcinoma with reference to C-thyroglobulin reaction of tumor cellsCancer, 1979
- Immunochemical and immunohistochemical studies on the 27 S iodoprotein of dog thyroid with reference to thyroglobulin-like reaction of the parafollicular cellsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1979
- C cell (parafollicular cell) ?Immunoreactive thyroglobulin: Purification, identification and immunological characterizationHistochemistry and Cell Biology, 1979
- The Identification of a Specific Fragment of Dog Thyroglobulin Responsible for Immunoreactivity to Parafollicular CellsEndocrinology, 1978
- Immunohistochemical study of a large molecular fragment of thyroglobulin in parafollicular cellsCell and tissue research, 1978
- Electron Microscopical and Immunohistochemical Study on Parafollicular Cell Complex with Reference to Parafollicular Cell as a ParaneuronArchivum histologicum japonicum, 1977
- Secretion by parafollicular cells beginning at birth: Ultrastructural evidence from developing canine thyroidJournal of Anatomy, 1976
- DONNÉES HISTOCHIMIQUES SUR LES CELLULES PARAFOLLICULAIRES DE LA GLANDE THYROSPACEDE DU CHIENCells Tissues Organs, 1959