Sympathetic Innervation of the Detrusor Muscle

Publisher Website
Google Scholar
Abstract
The authors investigated the distribution of sympathetic fibers in the vesical wall and tested the hypothesis that the detrusor muscle has an effective sympathetic innervation. The expts. were carried out in cats and dogs under nembutal anesthesia. The responses of the detrusor muscle were recorded kymographically under conditions (described in detail) designed to eliminate any effect of the record of responses elicited in the musculature at the base of the bladder. Faradic stimulation of the hypogastric nerves elicited an initial contraction followed by prolonged inhibition. Functional sympathetic innervation of the detrusor muscle, consequently, is demonstrated. The initial contraction of the detrusor muscle elicited by moderate sympathetic stimulation is of short duration and small amplitude; the following relaxation is prolonged but usually not very marked.