Synthesis of nitric oxide from l-arginine by neutrophils. Release and interaction with superoxide anion
- 1 July 1989
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 261 (1) , 293-296
- https://doi.org/10.1042/bj2610293
Abstract
Stimulated rat peritoneal neutrophils release a platelet inhibitory factor with the pharmacological properties of NO. This release is inhibited by NG-monomethyl-L-arginine and L-canavanine, indicating that it occurs through a mechanism similar to that in vascular endothelial cells and macrophages. As the degree of stimulation increases, the factor released is progressively inactivated by concomitant release of superoxide anions.This publication has 17 references indexed in Scilit:
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