INHIBITION OF ADRENALINE‐INDUCED PLATELET AGGREGATION BY THE α‐ADRENOCEPTOR BLOCKING DRUG BENEXTRAMINE
Open Access
- 1 June 1982
- journal article
- research article
- Published by Wiley in British Journal of Pharmacology
- Vol. 76 (2) , 253-257
- https://doi.org/10.1111/j.1476-5381.1982.tb09214.x
Abstract
1 The activity of the irreversible α-adrenoceptor blocking drug, benextramine, was determined in human platelets. 2 Compared to its postsynaptic and presynaptic α-adrenoceptor blocking potency, benextramine had a very low potency as an antagonist of adrenaline-induced platelet aggregation. 3 The results confirm the previous observation with the irreversible α-adrenoceptor blocking drug, phenoxybenzamine, that platelet α-adrenoceptors differ from postsynaptic and presynaptic α-adrenoceptors.This publication has 23 references indexed in Scilit:
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