Increased efficacy of an interleukin-12-secreting herpes simplex virus in a syngeneic intracranial murine glioma model
Open Access
- 1 July 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Neuro-Oncology
- Vol. 7 (3) , 213-224
- https://doi.org/10.1215/s1152851705000074
Abstract
Long-term survivors of glioblastoma multiforme, the most common form of primary intracranial malignancy in adults, are extremely rare. Experimental aKeywords
This publication has 28 references indexed in Scilit:
- Altered expression of antiviral cytokine mRNAs associated with cyclophosphamide's enhancement of viral oncolysisGene Therapy, 2004
- Effects of innate immunity on herpes simplex virus and its ability to kill tumor cellsGene Therapy, 2003
- Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trialGene Therapy, 2000
- Autocrine Growth Regulation by Granulocyte Colony-Stimulating Factor and Granulocyte Macrophage Colony-Stimulating Factor in Human Gliomas with Tumor ProgressionThe American Journal of Pathology, 1999
- Local production of TGF β1 inhibits cerebral edema, enhances TNF-α induced apoptosis and improves survival in a murine glioma modelJournal of Neuroimmunology, 1998
- Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukinsGene Therapy, 1998
- Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomasNature Medicine, 1995
- Cytokine gene expression on glioma cell lines and specimensJournal of Neuro-Oncology, 1994
- Reduction and Elimination of Encephalitis in an Experimental Glioma Therapy Model with Attenuated Herpes Simplex Mutants that Retain Susceptibility to AcyclovirNeurosurgery, 1993
- Resistance to Herpes Simplex Virus — Type 1 (HSV-1)Published by Springer Nature ,1981