THE FAT TOLERANCE TEST IN PITUITARY DISEASE

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Abstract
Examination of 109 individuals after a test meal showed absence of the physiological rise of blood acetone bodies in 56, mostly cases of pituitary deficiency. A rise was found in non-pituitary cases and in hypopituitary patients who had received prolonged specific organo-therapy. Cases (42) of lowered blood acetone after the test meal showed a low specific dynamic action; the blood uric acid averaged 3.9 mgm. %. Consistent combination of a low specific dynamic action, high uric acid and increased fat tolerance appears to characterize pituitary insufficiency.

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