Autoantibodies in iodide goitre and asthma.

  • 1 July 1966
    • journal article
    • Vol. 1  (3) , 285-96
Abstract
Thyroid and gastric autoimmunity occurred more frequently in patients with iodide goitre and those with intrinsic asthma than in patients with extrinsic asthma or age- and sex-matched controls. It is suggested that iodide administration is more likely to lead to goitre and hypothyroidism in the intrinsic asthmatic group, where latent thyroid autoimmunity is common, by aggravation of an existing organification defect in the thyroid. Latent Graves' disease recognized by failure of suppression of the thyroid radioiodine uptake by triiodothyronine may also be responsible for some cases of iodide goitre.