Construction of restriction maps
- 1 March 1988
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 4 (1) , 111-115
- https://doi.org/10.1093/bioinformatics/4.1.111
Abstract
A computer program is described, which constructs maps of restriction endonuclease cleavage sites in linear or circular DNA molecules, given the fragment lengths in single and double digestions with two enzymes. The algorithm is based upon a partition method and a very simple rule to chain fragments. The program is written in Prolog II.This publication has 2 references indexed in Scilit:
- Mapping the order of DNA restriction fragmentsGene, 1983
- Mapping of closed circular DNAs by cleavage with restriction endonucleases and calibration by agarose gel electrophoresis.Proceedings of the National Academy of Sciences, 1977