PERIODIC PARALYSIS ASSOCIATED WITH HYPERTHYROIDISM: REPORT OF THREE CASES

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Abstract
Since 1902, 35 cases of periodic paralysis with hyperthy-roidism were reported. Both the familial and sporadic types show flaccid paralysis with an abnormally low serum K level. Attacks can be induced with carbohydrates and insulin. The mechanism appears to be the loss or consumption of K in the metabolism of glycogen. This metabolism is profoundly affected by hyperthyroidism. All symptoms of paralysis disappear after control of the hyperthyroidism. Three cases of periodic paralysis associated with hyperthyroidism are presented. Follow-up extends up to 40 months following subtotal thyroidectomy.