Design and synthesis of dipeptidyl α′,β′-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain

This publication has 28 references indexed in Scilit:

• Cysteine Proteases and Their Inhibitors
  Chemical Reviews, 1997
• Investigation of the substrate specificity of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, through the use of cystatin-derived substrates and inhibitors
  Biochemical Journal, 1996
• Chapter 26. Regulation of Apoptosis by Members of the ICE Family and the Bcl-2 Family
  Published by Elsevier ,1996
• The Crystal Structure of Cruzain: A Therapeutic Target for Chagas' Disease
  Journal of Molecular Biology, 1995
• THE PROTEASES AND PATHOGENICITY OF PARASITIC PROTOZOA
  Annual Review of Microbiology, 1993
• Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi
  Molecular and Biochemical Parasitology, 1993
• Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites
  Biochemical Journal, 1992
• Refined x-ray structure of papain.E-64-c complex at 2.1-A resolution
  Published by Elsevier ,1991
• Papain Inhibitions by Optically Active E-64 Analogs
  The Journal of Biochemistry, 1981
• Structure and synthesis of E-64, a new thiol protease inhibitor.
  Agricultural and Biological Chemistry, 1978