GENESIS, a knowledge-based genetic engineering simulation system for represntation of genetic data and experiment planning
Open Access
- 1 January 1982
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (1) , 323-340
- https://doi.org/10.1093/nar/10.1.323
Abstract
We have built a knowledge-based genetic engineering simulation system-- GENESIS-- capable of representing both domain-specific and general knowledge. Information is stored within a hierarchically-organized framework composed of structures called units. A series of sophisticated editors enables non-computer specialist molecular geneticists to construct a knowledge base through direct interaction with the computer. Three types of knowledge specific to the domain of molecular genetics, MAPS, SEQUENCES and RULES are discussed in detail with examples.Keywords
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