Inhibition of the Immune Response to Whooping Cough and Tetanus Vaccines by Malaria Infection, and the Effect of Pertussis Adjuvant
- 1 May 1977
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 26 (3) , 520-524
- https://doi.org/10.4269/ajtmh.1977.26.520
Abstract
Plasmodium yoelii infection of mice depressed their capacity to build up humoral immune response to diphteria vaccine and protective immunity against tetanus toxin. This immunodepression was overcome by Freund's complete adjuvant or killed pertussis bacilli (whooping cough vaccine). These results suggest that vaccines should be given in association in malaria endemic area.This publication has 1 reference indexed in Scilit:
- Influence of Plasmodium berghei Infection on Susceptibility to Salmonella Infection.Experimental Biology and Medicine, 1965