COMPARATIVE INFLUENCE OF EPINEPHRINE AND OF DEXTROSE ON THE UTILIZATION OF SUGAR BY THE MUSCLES, DETERMINED WITH THE AID OF THERMOSTROMUHR MEASUREMENTS OF BLOOD FLOW

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Abstract
By use of the thermostromuhr of Rein the authors obtained actual rates of blood flow, under as nearly normal conditions as possible, in the hind limbs of dogs anesthetized with Na amytal. Employing these values for blood flow to convert the arteriovenous blood sugar differences into the amts. of sugar retained by the muscles per unit of time, they compared the utilization of sugar by the muscles during similar levels of hyperglycemia, caused by the administration of epinephrine and of dextrose respectively. They obtained no evidence that epinephrine decreases the utilization of sugar by the muscles. Similarly it was shown that the muscles continue to utilize sugar throughout a 7-hr. period of administration of epinephrine. These results completely confirm those obtained under less physiologic conditions with a simple flowmeter.

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