Patterns of CD8 T-Cell Epitopes within the Human Papillomavirus Type 16 (HPV 16) E6 Protein among Young Women Whose HPV 16 Infection Has Become Undetectable
Open Access
- 1 August 2005
- journal article
- Published by American Society for Microbiology in Clinical and Vaccine Immunology
- Vol. 12 (8) , 1003-1005
- https://doi.org/10.1128/cdli.12.8.1003-1005.2005
Abstract
The patterns of CD8 T-cell epitopes recognized within the E6 protein in women who had cleared their human papillomavirus 16 infection were examined. T-cell lines were established using autologous dendritic cells infected with a recombinant vaccinia virus. Evidence of potential antigenic epitopes was shown in 8 of 23 (34.8%) women.Keywords
This publication has 8 references indexed in Scilit:
- Spontaneous Regression of Grade 3 Vulvar Intraepithelial Neoplasia Associated with Human Papillomavirus-16–Specific CD4+ and CD8+ T-Cell ResponsesCancer Research, 2004
- Different Methods of Identifying New Antigenic Epitopes of Human Papillomavirus Type 16 E6 and E7 ProteinsClinical and Vaccine Immunology, 2004
- Amplification of low-frequency antiviral CD8 T cell responses using autologous dendritic cellsAIDS, 2002
- CD8+ lymphocytes respond to different HIV epitopes in seronegative and infected subjectsJournal of Clinical Investigation, 2001
- Persistence of Human Papillomavirus Type 16 Infection Is Associated with Lack of Cytotoxic T Lymphocyte Response to the E6 AntigensThe Journal of Infectious Diseases, 2000
- The natural history of human papillomavirus infection as measured by repeated DNA testing in adolescent and young womenThe Journal of Pediatrics, 1998
- Papillomavirus infections — a major cause of human cancersBiochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1996
- DETECTION AND TYPING OF GENITAL HUMAN PAPILLOMAVIRUSESPublished by Elsevier ,1990