Effect of desipramine injected intracerebrally in normal or reserpinized rats
- 1 April 1968
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 20 (4) , 293-296
- https://doi.org/10.1111/j.2042-7158.1968.tb09741.x
Abstract
Desipramine, 7·5–30 μg in 1 μl, injected under stereotaxic control into the brain of rats elicits a moderate hyperthermic response. This effect is more marked in animals made hypothermic by a previous treatment with reserpine. The response is not specific for any one of the six brain areas investigated (anterior part of the hypothalamus; nucleus rhomboideus thalami; third ventricle; posterior part of the hypothalamus; lateral part of the area amygdaloidea basalis; and lobus frontalis).This publication has 2 references indexed in Scilit:
- Peripheral and central components in the hyperthermic effect of desipramine in reserpinized ratsJournal of Pharmacy and Pharmacology, 1968
- Further effects of imipramine and its desmethyl derivative on the hypothermia induced by reserpineJournal of Pharmacy and Pharmacology, 1966