Thioredoxin‐interacting protein deficiency induces Akt/Bcl‐xL signaling and pancreatic beta‐cell mass and protects against diabetes
Open Access
- 13 June 2008
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 22 (10) , 3581-3594
- https://doi.org/10.1096/fj.08-111690
Abstract
Pancreatic beta‐cell loss through apoptosis represents a key factor in the pathogenesis of diabetes;however, no effective approaches to block this process and preserve endogenous beta‐cell mass are c...Keywords
Funding Information
- American Diabetes Association (7–07‐CD‐22)
- National Institutes of Health (R01DK‐078752)
- National Institutes of Health (R01HL‐51648)
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