PULMONARY EXCRETION OF CARBON-MONOXIDE IN THE HUMAN NEWBORN-INFANT AS AN INDEX OF BILIRUBIN PRODUCTION .3. MEASUREMENT OF PULMONARY EXCRETION OF CARBON-MONOXIDE AFTER THE 1ST POSTNATAL WEEK IN PREMATURE-INFANTS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 64  (5) , 598-600
Abstract
Using a single pass, flow-through system, the excretion rate of endogenously produced Co (.ovrhdot.VeCO) was measured as an index of bilirubin production in 41 Caucasian infants of various gestational ages after the 1st postnatal wk. Twenty-one were .ltoreq. 32 wk gestation. The mean slope for the 25 premature infants with multiple .ovrhdot.VeCO determinations was -0.21 .+-. 0.11 (SE) .mu.l/kg per h per day (P < 0.025, one-tailed). Fifteen premature infants with at least 3 .ovrhdot.VeCO determinations during the 1st 30 days of life had an average decrease in total CO excreted of 1.33% per day compared to the extrapolated initial value of total CO excretion of 27.0 .+-. 2.0 (SE) .mu.l/h, giving a calculated maximum red cell life span of 75 days.

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